Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 10/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263063 | 0.90 | CACNA1H (0.74) | CACNA1HPOLB | |
| SCHEMBL8225883 | 0.86 | CACNA1H (0.68) | CACNA1HPOLBGAACYP3A4CYP2D6 | |
| SCHEMBL8223718 | 0.85 | CACNA1H (0.83) | CACNA1HGAACYP2D6CYP2C9MEN1 | |
| SCHEMBL13595891 | 0.82 | CACNA1H (0.81) | CACNA1HGAACYP2D6CYP2C9MEN1 | |
| SCHEMBL8217909 | 0.79 | CACNA1H (0.69) | CACNA1HCYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL14263089 | 0.78 | CACNA1H (0.64) | CACNA1HPOLB | |
| SCHEMBL8223645 | 0.76 | CACNA1H (0.85) | CACNA1HCYP2D6CYP2C9MEN1KMT2A | |
| SCHEMBL8225899 | 0.76 | CACNA1H (0.52) | CACNA1HPOLB | |
| SCHEMBL8229860 | 0.76 | CACNA1H (0.56) | CACNA1HCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8228087 | 0.76 | CACNA1H (0.58) | CACNA1HGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033460-A2 | TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |