Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 10/20 | 0.78 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217909 | 0.92 | CACNA1H (0.69) | CACNA1HTRPV1 | |
| SCHEMBL8224175 | 0.91 | CACNA1H (0.86) | CACNA1HTRPV1 | |
| SCHEMBL13595981 | 0.90 | CACNA1H (0.84) | CACNA1HPANK3 | |
| SCHEMBL8226349 | 0.89 | CACNA1H (0.84) | CACNA1HTRPV1 | |
| SCHEMBL13595972 | 0.88 | CACNA1H (0.67) | CACNA1HTRPV1GRIN2BKMT2APANK3 | |
| SCHEMBL8218859 | 0.88 | CACNA1H (1.00) | CACNA1H | |
| SCHEMBL8226558 | 0.87 | CACNA1H (0.72) | CACNA1HTRPV1 | |
| SCHEMBL13595934 | 0.87 | CACNA1H (0.87) | CACNA1HKMT2APANK3 | |
| SCHEMBL8224721 | 0.86 | CACNA1H (0.67) | CACNA1HGRIN2BKMT2APOLB | |
| SCHEMBL8224751 | 0.85 | CACNA1H (0.84) | CACNA1HTRPV1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033460-A2 | TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |