Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 10/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226349 | 0.92 | CACNA1H (0.84) | CACNA1HTRPV1NPC1 | |
| SCHEMBL13595994 | 0.91 | CACNA1H (0.88) | CACNA1HLMNAMAPTHTT | |
| SCHEMBL8225905 | 0.87 | CACNA1H (0.78) | CACNA1HTRPV1 | |
| SCHEMBL8224175 | 0.86 | CACNA1H (0.86) | CACNA1HTRPV1NPC1SMN1; SMN2 | |
| SCHEMBL8217909 | 0.86 | CACNA1H (0.69) | CACNA1HTRPV1NPC1TP53RAB9A | |
| SCHEMBL13595934 | 0.85 | CACNA1H (0.87) | CACNA1HMAPTS1PR2 | |
| SCHEMBL13595976 | 0.84 | CACNA1H (1.00) | CACNA1HMAPT | |
| SCHEMBL8228087 | 0.82 | CACNA1H (0.58) | CACNA1HLMNATRPV1SMN1; SMN2 | |
| SCHEMBL8224721 | 0.82 | CACNA1H (0.67) | CACNA1HMAPTHTTSMN1; SMN2 | |
| SCHEMBL13595965 | 0.82 | CACNA1H (0.73) | CACNA1HSMN1; SMN2S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033460-A2 | TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |