Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810948 | 0.92 | LMNA (0.43) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL810947 | 0.92 | LMNA (0.43) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11410007 | 0.86 | MAPT (0.44) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11410032 | 0.86 | MAPT (0.44) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL820799 | 0.82 | LMNA (0.42) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL820800 | 0.82 | LMNA (0.42) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL821999 | 0.82 | LMNA (0.41) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL822000 | 0.82 | LMNA (0.41) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL21357364 | 0.80 | ALDH1A1 (0.39) | LMNAGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12955462 | 0.80 | ALDH1A1 (0.39) | LMNAGAAALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | disclosed |