Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.68 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715059 | 0.86 | PCSK9 (0.55) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28605628 | 0.86 | ALDH1A1 (0.58) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11888326 | 0.85 | PCSK9 (0.53) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29588739 | 0.83 | CYP3A4 (0.52) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15591050 | 0.82 | PCSK9 (0.52) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15591266 | 0.82 | PCSK9 (0.52) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL715058 | 0.79 | PCSK9 (0.49) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14667460 | 0.79 | PCSK9 (0.48) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10939353 | 0.78 | PCSK9 (0.47) | PCSK9NQO2KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6486776 | 0.78 | NQO2 (0.50) | PCSK9NQO2KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11189806-B2 | Heteroleptic carbene complexes and the use thereof in organic electronics | UDC IRELAND LIMITED (IE) | 2021-11-30 | — | — | US | disclosed |
| US-20210126207-A1 | Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS | UDC IRELAND LTD (IE) | 2021-04-29 | — | — | US | disclosed |
| EP-3052229-B1 | IMMOBILIZED METATHESIS TUNGSTEN OXO ALKYLIDENE CATALYSTS AND USE THEREOF IN OLEFIN METATHESIS | VERBIO VER BIOENERGIE AG (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-10916716-B2 | Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS | UDC IRELAND LIMITED (IE) | 2021-02-09 | — | — | US | disclosed |
| US-20200373503-A1 | HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2020-11-26 | — | — | US | disclosed |
| EP-2590967-B1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | UDC IRELAND LTD (IE) | 2019-05-15 | — | — | EP | disclosed |
| EP-2393819-B9 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | UDC IRELAND LTD (IE) | 2017-12-27 | — | — | EP | disclosed |
| US-9850268-B2 | Metathesis catalysts and methods thereof | TRUSTEES OF BOSTON COLLEGE (US) | 2017-12-26 | — | — | US | disclosed |
| US-9701702-B2 | Metathesis catalysts and methods thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2393819-B1 | SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-1626999-B1 | OLEFIN POLYMERIZATION CATALYST SYSTEM USEFUL FOR POLAR MONOMERS | EXXONMOBIL CHEM PATENTS INC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070197751-A1 | Olefin polymerization catalyst system useful for polar monomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197751-A1 | Olefin polymerization catalyst system useful for polar monomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-08-23 | — | — | US | disclosed |
| EP-1288710-A1 | Thermally developable infrared sensitive imaging materials containing heat-bleachable antihalation composition | EASTMAN KODAK COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6514677-B1 | Thermally developable infrared sensitive imaging materials containing heat-bleachable antihalation composition | EASTMAN KODAK COMPANY | 2003-02-04 | — | — | US | disclosed |
| US-5676884-A | Nonlinear optical materials containing polar disulfone-functionalized molecules | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-14 | — | — | US | disclosed |
| US-5578251-A | NONLINEAR-OPTICAL RESPONSE; ALKYLATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5360582-A | Compositions with polymers for light sensitive elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0594697-A1 | NONLINEAR OPTICAL MATERIALS CONTAINING POLAR DISULFONE-FUNCTIONALIZED MOLECULES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993002383-A1 | NONLINEAR OPTICAL MATERIALS CONTAINING POLAR DISULFONE-FUNCTIONALIZED MOLECULES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210126207-A1 | Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS | OCIAD1, OCIAD2, DRD2 | PCSK9 4362/4885NQO2 3261/4885KMT2A 4549/4885 |
| US-20200373503-A1 | HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS | OCIAD2, OCIAD1, CLTB | PCSK9 4824/4885NQO2 2152/4885KMT2A 2077/4885 |
| US-11189806-B2 | Heteroleptic carbene complexes and the use thereof in organic electronics | OCIAD2, OCIAD1, CLTB | PCSK9 4824/4885NQO2 2152/4885KMT2A 2077/4885 |
| US-10916716-B2 | Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS | OCIAD1, OCIAD2, DRD2 | PCSK9 4362/4885NQO2 3261/4885KMT2A 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.