Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20880646 | 0.83 | P2RX7 (0.37) | P2RX7FAAHHSP90AA1HKDC1GRM4 | |
| SCHEMBL21953560 | 0.76 | KDM4E (0.48) | HSP90AA1 | |
| SCHEMBL27460117 | 0.72 | P2RX7 (0.46) | P2RX7FAAHHSP90AA1HKDC1GRM4 | |
| SCHEMBL8231887 | 0.72 | L3MBTL1 (0.39) | — | |
| SCHEMBL15943062 | 0.72 | P2RX7 (0.46) | P2RX7FAAHHSP90AA1HKDC1GRM4 | |
| SCHEMBL8235146 | 0.71 | P2RX7 (0.36) | P2RX7FAAHHSP90AA1HKDC1GRM4 | |
| SCHEMBL28021894 | 0.70 | — | — | |
| SCHEMBL13134207 | 0.70 | — | — | |
| SCHEMBL13243144 | 0.70 | P2RX7 (0.38) | P2RX7FAAHGRM4 | |
| SCHEMBL28026231 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119463-A1 | 2-(CYCLIC AMINO)-PYRIMIDONE DERIVATIVES AS TPK1 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-10-25 | — | — | WO | disclosed |