Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665556 | 1.00 | GFER (0.72) | GFERALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL13028454 | 0.96 | GFER (0.67) | GFERALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL3559760 | 0.92 | HDAC1 (0.64) | GFERALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL3562112 | 0.92 | TSHR (0.67) | GFERALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL4090549 | 0.88 | MAPT (0.70) | ALDH1A1LMNAGAAMAPK1PGR | |
| SCHEMBL1279147 | 0.88 | PLAU (0.72) | ALDH1A1LMNAGAAMAPK1PGR | |
| SCHEMBL12338860 | 0.88 | GFER (0.86) | GFERALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL790294 | 0.87 | GAA (0.86) | GFERALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL5457275 | 0.87 | POLB (0.72) | ALDH1A1LMNAGAAMAPK1PGR | |
| SCHEMBL9319934 | 0.87 | LMNA (0.66) | ALDH1A1LMNAGAAMAPK1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144379-A1 | BICYCLIC COMPOUNDS USEFUL AS CATHEPSIN S INBHIBITORS | MEDIVIR AB (SE) | 2007-12-21 | — | — | WO | disclosed |