SCHEMBL790294

SCHEMBL790294

COc1ccc(NS(=O)(=O)c2ccc(OC)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.86
MAPK1 P28482 2/20 0.86
LMNA P02545 2/20 0.86
ALDH1A1 P00352 6/20 0.78
PGR P06401 1/20 0.78
CYP19A1 P11511 1/20 0.74
PKM P14618 4/20 0.73
MAPT P10636 4/20 0.71
SMN1; SMN2 Q16637 3/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
KDM4E B2RXH2 1/20 0.71
BLM P54132 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
GFER P55789 1/20 0.71
TSHR P16473 1/20 0.69
HTT P42858 1/20 0.69
KEAP1 Q14145 1/20 0.69
NFE2L2 Q16236 1/20 0.69
PLAU P00749 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679643 0.94 GAA (0.78) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL30434229 0.93 GAA (0.76) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL806437 0.93 GAA (0.76) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL7564170 0.93 GAA (0.76) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL29031235 0.93 PGR (0.85) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL6301477 0.91 GAA (0.73) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL2240982 0.91 LMNA (0.73) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL16116950 0.91 GAA (0.73) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL789993 0.91 PPIA (0.79) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL8752410 0.91 GAA (0.73) GAAMAPK1LMNAALDH1A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
EP-3131658-B1 IMPROVED SULFUR RECOVERY PROCESS FOR TREATING LOW TO MEDIUM MOLE PERCENT HYDROGEN SULFIDE GAS FEEDS WITH BTEX IN A CLAUS UNIT SAUDI ARABIAN OIL CO (SA) 2019-09-25 EP disclosed
US-9981848-B2 Sulfur recovery process for treating low to medium mole percent hydrogen sulfide gas feeds with BTEX in a claus unit SAUDI ARABIAN OIL COMPANY (SA) 2018-05-29 US disclosed
US-20170137288-A1 SULFUR RECOVERY PROCESS FOR TREATING LOW TO MEDIUM MOLE PERCENT HYDROGEN SULFIDE GAS FEEDS WITH BTEX IN A CLAUS UNIT SAUDI ARABIAN OIL COMPANY (SA) 2017-05-18 US disclosed
US-9593015-B2 Sulfur recovery process for treating low to medium mole percent hydrogen sulfide gas feeds with BTEX in a Claus unit SAUDI ARABIAN OIL COMPANY (SA) 2017-03-14 US disclosed
EP-3131658-A1 IMPROVED SULFUR RECOVERY PROCESS FOR TREATING LOW TO MEDIUM MOLE PERCENT HYDROGEN SULFIDE GAS FEEDS WITH BTEX IN A CLAUS UNIT Saudi Arabian Oil Company (SA) 2017-02-22 EP disclosed
US-9212134-B2 Inhibitors of viral entry into mammalian cells MICROBIOTIX, INC. (US) 2015-12-15 US disclosed
US-9212134-B2 Inhibitors of viral entry into mammalian cells MICROBIOTIX, INC. (US) 2015-12-15 US disclosed
WO-2015160645-A1 IMPROVED SULFUR RECOVERY PROCESS FOR TREATING LOW TO MEDIUM MOLE PERCENT HYDROGEN SULFIDE GAS FEEDS WITH BTEX IN A CLAUS UNIT SAUDI ARABIAN OIL COMPANY (SA) 2015-10-22 WO disclosed
WO-2006028529-A2 IONIC POLYMER MEMBRANES BP CORPORATION NORTH AMERICA INC. (US) 2006-03-16 WO disclosed
US-20060049102-A1 Ionic polymer membranes BP CORPORATION NORTH AMERICA INC. 2006-03-09 US disclosed
US-20030191309-A1 N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production HO WEN-BIN (US) 2003-10-09 US disclosed
US-6579343-B2 Contacting gas with a liquid ionic compound comprising a nitrogen-containing heterocyclic cation UNIVERSITY OF NOTRE DAME DU LAC 2003-06-17 US disclosed
US-6506936-B1 Treating fibrotic disorder selected from hepatic cirrhosis and arthritis; inhibiting matrix metalloproteases FIBROGEN, INC. 2003-01-14 US disclosed
US-20020189444-A1 Purification of gas with liquid ionic compounds NATIONAL SCIENCE FOUNDATION 2002-12-19 US disclosed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US disclosed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191309-A1 N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of C-proteinase and for treating or preventing disorders related to unregulated collagen production MMP1, MMP13, COL14A1 GAA 417/4885MAPK1 2792/4885LMNA 779/4885
US-20170137288-A1 SULFUR RECOVERY PROCESS FOR TREATING LOW TO MEDIUM MOLE PERCENT HYDROGEN SULFIDE GAS FEEDS WITH BTEX IN A CLAUS UNIT MST1, MSTN, TST GAA 3813/4885MAPK1 1474/4885LMNA 4370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.