Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648069 | 0.90 | KMT2A (0.43) | KMT2AMAPTMEN1LMNACYP2C9 | |
| SCHEMBL8236417 | 0.84 | RAB9A (0.51) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL8234100 | 0.84 | RAB9A (0.48) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL8067234 | 0.84 | RAB9A (0.45) | KMT2AMAPTMEN1RAB9ANPC1 | |
| SCHEMBL8237123 | 0.81 | MAPT (0.51) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL8234426 | 0.81 | RAB9A (0.45) | KMT2AMAPTLMNARAB9ANPC1 | |
| SCHEMBL3103400 | 0.81 | RAB9A (0.45) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL8236747 | 0.80 | NPC1 (0.46) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL646343 | 0.80 | RAB9A (0.49) | KMT2AMAPTMEN1LMNARAB9A | |
| SCHEMBL8238174 | 0.79 | RAB9A (0.48) | KMT2AMAPTLMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109362-A2 | BENZOIMIDAZOLYL-PARAZINE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-09-27 | — | — | WO | disclosed |