Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328979 | 0.87 | FAAH (0.41) | FAAHUSP30UCHL1PDE4DALDH1A3 | |
| Hydrochloric Acid SCHEMBL5327767 | 0.86 | FAAH (0.40) | FAAHUSP30UCHL1PDE4DALDH1A3 | |
| SCHEMBL8227245 | 0.78 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL8227701 | 0.78 | CA12 (0.33) | — | |
| SCHEMBL5333174 | 0.77 | ALDH1A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL5324966 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL8222376 | 0.75 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL8230910 | 0.75 | ALDH1A1 (0.36) | FAAHUSP30UCHL1 | |
| SCHEMBL8228991 | 0.75 | JAK2 (0.33) | UCHL1 | |
| SCHEMBL8221773 | 0.73 | PIM1 (0.35) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148113-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-12-27 | — | — | WO | disclosed |