Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033958 | 0.89 | TYR (0.46) | TYRACACBGPR84POLBDRD2 | |
| SCHEMBL30910238 | 0.87 | GPR84 (0.47) | TYRACACBGPR84DRD2DRD3 | |
| SCHEMBL13677546 | 0.84 | POLB (0.46) | ACACBGPR84POLBDRD2DRD3 | |
| SCHEMBL5005631 | 0.80 | ACACB (0.44) | ACACBDRD2DRD3HSD17B13MEN1 | |
| SCHEMBL1038378 | 0.80 | GRM2 (0.41) | POLBGRM2ALDH1A1 | |
| SCHEMBL17563249 | 0.78 | TYR (0.41) | TYRACACBPOLBDRD2DRD3 | |
| SCHEMBL18186968 | 0.77 | ACACB (0.39) | TYRACACBGRM2GAA | |
| SCHEMBL16762467 | 0.77 | SMN1; SMN2 (0.43) | TYRACACBGRM2KDM4EALDH1A1 | |
| SCHEMBL256009 | 0.77 | MAP2K2 (0.41) | TYRACACBGRM2MCHR1KCNH2 | |
| SCHEMBL9099862 | 0.77 | POLB (0.36) | GPR84POLBDRD2DRD3HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007083978-A1 | IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CRYSTALGENOMICS, INC. (KR) | 2007-07-26 | — | — | WO | disclosed |