Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231175 | 0.82 | ABCC4 (0.48) | ALDH1A1LMNAMAPTABCC4 | |
| SCHEMBL7364154 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNARECQLMAPTTET2 | |
| SCHEMBL13538038 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNARECQLMAPTTET2 | |
| SCHEMBL8230419 | 0.75 | ALDH1A1 (0.65) | ALDH1A1LMNARECQLMAPTTET2 | |
| SCHEMBL13948785 | 0.75 | ALDH1A1 (0.65) | ALDH1A1LMNARECQLMAPTTET2 | |
| SCHEMBL27298904 | 0.72 | ALDH1A1 (0.55) | ALDH1A1LMNARECQLMAPTTET2 | |
| SCHEMBL21911888 | 0.72 | TET2 (0.45) | ALDH1A1LMNARECQLTET2SMN1; SMN2 | |
| SCHEMBL629595 | 0.71 | ALDH1A1 (0.36) | ALDH1A1LMNARECQLMAPTUSP2 | |
| SCHEMBL515390 | 0.70 | ALDH1A1 (0.96) | ALDH1A1LMNARECQLMAPTABCC4 | |
| SCHEMBL14639272 | 0.69 | ABCC4 (0.37) | ALDH1A1LMNAMAPTABCC4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148135-A1 | MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-27 | — | — | WO | disclosed |