Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | DRD4 | P21917 | 8/20 | 0.49 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | IL4I1 | Q96RQ9 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277851 | 0.88 | CACNA2D1 (0.49) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL8229361 | 0.86 | NPC1 (0.41) | DRD2DRD4DRD3SMN1; SMN2MAPT | |
| SCHEMBL13609767 | 0.81 | DRD2 (0.47) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL4271450 | 0.80 | DRD2 (0.73) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL4271439 | 0.78 | DRD2 (0.46) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL4276453 | 0.78 | DRD2 (0.45) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL4283221 | 0.78 | DRD2 (0.45) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL13625846 | 0.76 | SMN1; SMN2 (0.53) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL4307364 | 0.76 | NOTUM (0.56) | DRD2DRD4DRD3NOTUMSMN1; SMN2 | |
| SCHEMBL4283254 | 0.76 | DRD2 (0.44) | DRD2DRD4DRD3NOTUMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118323-A1 | ISOXAZOLE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD. (CA) | 2007-10-25 | — | — | WO | disclosed |