Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 9/20 | 0.52 |
| ▸ | DRD4 | P21917 | 9/20 | 0.52 |
| ▸ | DRD3 | P35462 | 9/20 | 0.52 |
| ▸ | IL4I1 | Q96RQ9 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307364 | 0.86 | NOTUM (0.56) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL8577214 | 0.84 | DRD2 (0.56) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL12420831 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL4271450 | 0.81 | DRD2 (0.73) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL7650321 | 0.80 | PRMT5 (0.53) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL13616467 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL1316671 | 0.79 | NOTUM (0.55) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL1316937 | 0.79 | NOTUM (0.55) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL12112325 | 0.78 | IL4I1 (0.52) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 | |
| SCHEMBL8229282 | 0.76 | DRD2 (0.49) | SMN1; SMN2MAPTNOTUMCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137380-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-12 | — | — | WO | disclosed |