Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053935 | 0.84 | MAPK1 (0.38) | RENMAPK1KMO | |
| SCHEMBL8223910 | 0.82 | MAPK1 (0.39) | RENMAPK1KMO | |
| SCHEMBL5324540 | 0.82 | MAPK1 (0.39) | RENMAPK1KMO | |
| SCHEMBL3779683 | 0.78 | ITGA4 (0.43) | RENMAPK1KMO | |
| SCHEMBL12053933 | 0.78 | MAPK1 (0.40) | RENMAPK1KMO | |
| SCHEMBL8223918 | 0.78 | MAPK1 (0.41) | RENMAPK1KMO | |
| SCHEMBL3786556 | 0.76 | KMO (0.45) | RENMAPK1KMO | |
| SCHEMBL12053964 | 0.76 | MAPK1 (0.38) | RENMAPK1 | |
| SCHEMBL3775268 | 0.75 | MAPK1 (0.41) | RENMAPK1KMO | |
| SCHEMBL3775264 | 0.75 | MAPK1 (0.41) | RENMAPK1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120523-A2 | 6-(AMINOALKYL)INDAZOLES | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |