Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 1.00 |
| ▸ | CA4 | P22748 | 2/20 | 1.00 |
| ▸ | CA1 | P00915 | 14/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL6123440 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL28946409 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL431405 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL27711371 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL29175054 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL29053363 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL16115635 | 1.00 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL5865919 | 0.97 | CA2 (0.94) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL9279060 | 0.97 | CA2 (0.94) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL20975494 | 0.97 | CA2 (0.94) | CA2CA4CA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 288128 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144755-A1 | Solid Oral Dosage Forms Comprising Tavapadon | CEREVEL THERAPEUTICS, LLC (US) | 2026-05-28 | — | — | US | claimed |
| US-20260144723-A1 | HAIR CLEANSER FORMULATION FOR TEXTURED HAIR | TheKlayCo. LLC (US) | 2026-05-28 | — | — | US | claimed |
| EP-4319591-B1 | AN ELASTOMERIC ARTICLE | MATANG MFG SDN BHD (MY) | 2026-05-27 | — | — | EP | claimed |
| CN-122075378-A | Antioxidant composition and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-121873800-B | Alkali polishing additive, polishing solution and polishing method | Jiageng Innovation Laboratory (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122075328-A | Dentifrice with whitening, tooth stain removing and anti-inflammatory effects and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-12636289-B2 | Lamotrigine oral liquid suspension and use thereof | OWP Pharmaceuticals, Inc. (US) | 2026-05-26 | — | — | US | claimed |
| CN-122075360-A | Shampoo care composition containing red alga palmleaf tree extract and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-113262186-B | Composition for deodorizing and freshening breath and application thereof in oral care products | Guangzhou Jingshen Cosmetics Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122075394-A | Ionizing radiation protective adhesive and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-3990978-A | ALUMINUM SALT OF PHOSPHATE ESTER | THE DOW CHEMICAL COMPANY (US) | 1976-11-09 | — | — | US | claimed |
| US-3989640-A | SYNERGISTIC, MORPHOLINE, AMMONIUM BENZOATE AND CYCLOHEXANE OR NITROPROPANE OR CYCLOPENTENE | THE DRACKETT COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-3985890-A | Pickled seafood | BROWN ETHEL A | 1976-10-12 | — | — | US | claimed |
| US-3962189-A | PROCESS AND CATALYST-INHIBITOR SYSTEMS FOR PREPARING SYNTHETIC LINEAR POLYESTERS | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | claimed |
| US-3962384-A | Spray-drying technique for preparing agglomerated powders | HOFFMANN-LA ROCHE INC. (US) | 1976-06-08 | — | — | US | claimed |
| US-3952063-A | Process for the preparation of an organomercaptophenol from sulfur, a phenol, and an activated olefin or an epoxy compound | GENERAL ELECTRIC COMPANY (US) | 1976-04-20 | — | — | US | claimed |
| US-3947570-A | MOUTHWASH, LEMON OIL | COLGATE-PALMOLIVE COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-3935324-A | FAT, LECITHIN, SUGAR, WATER | AB KARLSHAMNS OLJEFABRIKER (SW) | 1976-01-27 | — | — | US | claimed |
| US-3932207-A | Process for obtaining cellulose from ligno-cellulosic raw materials | SOCIETE DE PROMOTION ET D'EXPLOITATION INDUSTRIELLES DE PROCEDES DE BREVETS S.A. (CH) | 1976-01-13 | — | — | US | claimed |
| US-3932316-A | PHOSPHATE-FREE | THE PROCTER & GAMBLE COMPANY (US) | 1976-01-13 | — | — | US | claimed |