Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.94 |
| ▸ | CA4 | P22748 | 2/20 | 0.94 |
| ▸ | CA1 | P00915 | 14/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL431405 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL823 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL27711371 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL28946409 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL29175054 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL6123440 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL16115635 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL29053363 | 0.97 | CA2 (1.00) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL16872747 | 0.94 | CA2 (0.94) | CA2CA4CA1CES2CES1 | |
| Benzoic Acid SCHEMBL11057024 | 0.94 | CA2 (0.94) | CA2CA4CA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336473-A | Waterborne soil binder | 天津美士邦涂料化工有限公司 | 2017-01-18 | — | — | CN | claimed |
| US-20250064996-A1 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. | 2025-02-27 | — | — | US | disclosed |
| EP-4023249-B1 | NUCLEIC ACID VACCINES | MODERNATX INC (US) | 2024-10-09 | — | — | EP | disclosed |
| EP-0539579-A1 | DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES | The Lubrizol Corporation (US) | 1993-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250064996-A1 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | TFRC, SLC39A14, EGFR | CA2 2085/4885CA4 670/4885CA1 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.