Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979217 | 0.92 | HPGD (0.40) | CCR4KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8229731 | 0.86 | F10 (0.39) | ALDH1A1F10MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8230002 | 0.82 | F10 (0.41) | CCR4KMT2AALDH1A1F10MAPT | |
| SCHEMBL3982271 | 0.79 | F10 (0.41) | KMT2AKDM4EALDH1A1ALOX15TDP1 | |
| SCHEMBL8225135 | 0.78 | F10 (0.55) | CCR4KMT2AALDH1A1F10MAPT | |
| SCHEMBL3377662 | 0.78 | HPGD (0.44) | KMT2AKDM4EALDH1A1F10MEN1 | |
| SCHEMBL3381006 | 0.77 | F10 (0.45) | KMT2AKDM4EALDH1A1F10MAPT | |
| SCHEMBL3986630 | 0.74 | HTT (0.45) | KMT2AKDM4EALDH1A1L3MBTL1F10 | |
| SCHEMBL3987347 | 0.73 | F10 (0.47) | KMT2AKDM4EALDH1A1F10MAPT | |
| SCHEMBL13070183 | 0.72 | ALDH1A1 (0.37) | KMT2AKDM4EALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |