SCHEMBL823003

SCHEMBL823003

CCCOC(C)P1(=O)OCC(C)(C)CO1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13867083 0.73 CYP1A2 (0.32) CYP1A2CYP3A4GAACYP2C9CYP2C19
SCHEMBL13867139 0.71 CYP1A2 (0.32) CYP1A2CYP3A4GAACYP2C9CYP2C19
SCHEMBL28243499 0.70 CYP1A2 (0.36) CYP1A2CYP3A4GAACYP2C9CYP2C19
SCHEMBL817189 0.67
SCHEMBL19386904 0.64 CYP1A2 (0.32) CYP1A2CYP3A4GAACYP2C9CYP2C19
SCHEMBL13471387 0.64 CYP1A2 (0.32) CYP1A2CYP3A4GAACYP2C9CYP2C19
SCHEMBL16903717 0.63
SCHEMBL17860962 0.63 ALDH1A1 (0.35) CYP1A2CYP3A4GAACYP2C9CYP2C19
SCHEMBL8495042 0.63 LMNA (0.32)
SCHEMBL17860891 0.63 CYP1A2 (0.30) CYP1A2CYP3A4GAACYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8058322-B2 Flame-retardant flexible polyurethane foam ICL-IP AMERICA INC. (US) 2011-11-15 US disclosed
US-20090281205-A1 Flame-retardant flexible polyurethane foam ICL-IP AMERICA INC. 2009-11-12 US disclosed