SCHEMBL8230353

SCHEMBL8230353

CCCCCCCCCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(N)=O)C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NCC(=O)NC(CCCN)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NCC(=O)NC(CO)C(=O)NC(C(=O)NC(CC(=O)c1ccccc1N)C(=O)O)C(C)CC(=O)O)C(C)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 12/20 0.56
ECE1 P42892 1/20 0.55
MUS81 Q96NY9 1/20 0.55
GCGR P47871 1/20 0.53
GIPR P48546 1/20 0.53
RXFP1 Q9HBX9 3/20 0.52
CXCR4 P61073 1/20 0.51
ERBB2 P04626 1/20 0.50
CCKBR P32239 2/20 0.50
CCKAR P32238 1/20 0.50
OPRD1 P41143 1/20 0.50
PRMT1 Q99873 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24625800 1.00 GLP1R (0.56) GLP1RECE1MUS81GCGRGIPR
SCHEMBL12124805 0.94 GLP1R (0.53) GLP1RECE1MUS81GCGRGIPR
SCHEMBL92822 0.90 PRMT1 (0.55) GLP1RECE1MUS81CXCR4ERBB2
SCHEMBL26236645 0.88 GLP1R (0.46) GLP1RECE1MUS81GCGRGIPR
SCHEMBL8227196 0.86 CCKAR (0.56) GLP1RGCGRGIPRERBB2CCKBR
SCHEMBL16690458 0.85 GLP1R (0.46) GLP1RECE1MUS81GCGRRXFP1
SCHEMBL29679760 0.81 GLP1R (0.65) GLP1RECE1MUS81RXFP1CCKBR
SCHEMBL29679523 0.81 GLP1R (0.69) GLP1RECE1MUS81RXFP1CCKBR
SCHEMBL10157514 0.81 CCKBR (0.54) ERBB2CCKBRCCKAROPRD1PRMT1
SCHEMBL26080290 0.81 NPBWR1 (0.58) GLP1RRXFP1CCKBRCCKAROPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2504353-B2 LIPOPEPTIDE COMPOSITIONS AND RELATED METHODS CUBIST PHARMACEUTICALS LLC (CH) 2023-09-13 EP disclosed
US-7335726-B2 Lipopeptide stereoisomers, methods for preparing same and useful intermediates CUBIST PHARMACEUTICALS, INC. (US) 2008-02-26 US disclosed
US-7262268-B2 Lipopeptide stereoisomers, methods for preparing same, and useful intermediates CUBIST PHARMACEUTICALS, INC. (US) 2007-08-28 US disclosed
US-20060223983-A1 Lipopeptide stereoisomers, methods for preparing same and useful intermediates CUBIST PHARMACEUTICALS, INC. 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223983-A1 Lipopeptide stereoisomers, methods for preparing same and useful intermediates NGLY1, LSS, NRDC GLP1R 305/4885ECE1 3407/4885MUS81 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.