Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028167 | 0.69 | DPP4 (0.55) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL17814216 | 0.62 | DPP4 (0.55) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL3226030 | 0.61 | DPP4 (0.44) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL3226022 | 0.61 | DPP4 (0.44) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8013071 | 0.60 | DPP4 (0.49) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8395791 | 0.59 | EPHX1 (0.37) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8226158 | 0.59 | DPP4 (0.50) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8026012 | 0.59 | DPP4 (0.50) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL26025241 | 0.59 | DPP4 (0.50) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL20124270 | 0.59 | EPHX1 (0.38) | DPP4TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100374-A9 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TUFTS COLLEGE (US) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007100374-A2 | SOFT PROTEASE INHIBITORS AND PRO-SOFT FORMS THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2007-09-07 | — | — | WO | disclosed |