Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.68 |
| ▸ | ITK | Q08881 | 4/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230677 | 0.94 | ADORA2A (0.68) | ADORA2AITK | |
| SCHEMBL8233912 | 0.92 | ADORA2A (0.79) | ADORA2AITKEHMT2 | |
| SCHEMBL12744854 | 0.89 | ADORA2A (0.85) | ADORA2AITK | |
| SCHEMBL8247059 | 0.87 | ADORA2A (0.81) | ADORA2A | |
| SCHEMBL8230880 | 0.86 | ADORA2A (0.75) | ADORA2AITK | |
| SCHEMBL8225590 | 0.85 | EHMT2 (0.66) | ADORA2AITKEHMT2 | |
| SCHEMBL8230877 | 0.85 | ADORA2A (0.79) | ADORA2AITK | |
| SCHEMBL8239545 | 0.85 | ADORA2A (0.61) | ADORA2AITK | |
| SCHEMBL8240280 | 0.85 | ADORA2A (0.76) | ADORA2A | |
| SCHEMBL8232572 | 0.84 | ADORA2A (0.69) | ADORA2AITKEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |