Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.68 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230504 | 0.94 | ADORA2A (0.68) | ADORA2AITK | |
| SCHEMBL8230880 | 0.93 | ADORA2A (0.75) | ADORA2AITKOPRK1IRAK4 | |
| SCHEMBL8230877 | 0.92 | ADORA2A (0.79) | ADORA2AITKOPRK1IRAK4 | |
| SCHEMBL1468392 | 0.89 | ADORA2A (0.85) | ADORA2AITKOPRK1 | |
| SCHEMBL8239545 | 0.86 | ADORA2A (0.61) | ADORA2AITK | |
| SCHEMBL8247059 | 0.86 | ADORA2A (0.81) | ADORA2A | |
| SCHEMBL8233532 | 0.85 | ADORA2A (0.65) | ADORA2AITKOPRK1 | |
| SCHEMBL8230882 | 0.85 | ADORA2A (0.65) | ADORA2AITKOPRK1 | |
| SCHEMBL8233912 | 0.85 | ADORA2A (0.79) | ADORA2AITKOPRK1 | |
| SCHEMBL8240280 | 0.83 | ADORA2A (0.76) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |