Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230877 | 0.97 | ADORA2A (0.79) | ADORA2AOPRK1CNR2ITKIRAK4 | |
| SCHEMBL8230677 | 0.93 | ADORA2A (0.68) | ADORA2AOPRK1ITKIRAK4 | |
| SCHEMBL8233912 | 0.91 | ADORA2A (0.79) | ADORA2AOPRK1CNR2ITK | |
| SCHEMBL8230882 | 0.91 | ADORA2A (0.65) | ADORA2AOPRK1ITK | |
| SCHEMBL8233532 | 0.91 | ADORA2A (0.65) | ADORA2AOPRK1ITK | |
| SCHEMBL1468271 | 0.88 | ADORA2A (0.95) | ADORA2AOPRK1ITK | |
| SCHEMBL12744804 | 0.86 | ADORA2A (1.00) | ADORA2AOPRK1ITK | |
| SCHEMBL8230504 | 0.86 | ADORA2A (0.68) | ADORA2AITK | |
| SCHEMBL8246362 | 0.86 | ADORA2A (0.57) | ADORA2A | |
| SCHEMBL8247595 | 0.85 | ADORA2A (0.76) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133983-A2 | 2-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-11-22 | — | — | WO | disclosed |