Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713173 | 0.85 | P2RX7 (0.47) | P2RX7POLBGAANPC1RAB9A | |
| SCHEMBL18724905 | 0.82 | NOTUM (0.39) | P2RX7POLBGAANPC1RAB9A | |
| SCHEMBL23227311 | 0.80 | NOTUM (0.42) | P2RX7POLBGAAPARP1PARP2 | |
| SCHEMBL3069589 | 0.79 | EPHX1 (0.47) | P2RX7POLBGAAKMT2AALDH1A1 | |
| SCHEMBL23489029 | 0.77 | NPSR1 (0.45) | P2RX7POLBNPC1RAB9AKMT2A | |
| SCHEMBL23489024 | 0.77 | NPSR1 (0.45) | P2RX7POLBNPC1RAB9AKMT2A | |
| SCHEMBL25639171 | 0.76 | P2RX7 (0.38) | P2RX7POLBGAANPC1RAB9A | |
| SCHEMBL18184634 | 0.76 | PARP1 (0.37) | P2RX7PARP1 | |
| SCHEMBL18724830 | 0.75 | KDM5A (0.42) | POLBNPC1RAB9AKMT2A | |
| SCHEMBL1583858 | 0.74 | TP53 (0.44) | P2RX7KMT2AALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007127135-A2 | ANTIBIOTIC COMPOUNDS | MERCK & CO., INC. (US) | 2007-11-08 | — | — | WO | disclosed |