Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3984316 | 0.99 | F10 (0.48) | F10NCF1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL671170 | 0.86 | F10 (0.47) | F10PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL7895104 | 0.86 | MAP4K1 (0.53) | F10PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL670900 | 0.86 | MAP4K1 (0.50) | F10PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL3864241 | 0.85 | F10 (0.60) | F10PTGS2 | |
| SCHEMBL29740650 | 0.82 | PIK3CD (0.49) | F10PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL20124865 | 0.82 | PIK3CD (0.49) | F10PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL13853420 | 0.79 | HTR1A (0.46) | F10NCF1AGXT | |
| Hydrochloric Acid SCHEMBL4234312 | 0.78 | HTR1A (0.45) | F10NCF1AGXT | |
| SCHEMBL2940366 | 0.78 | MAP4K1 (0.50) | F10PIK3CDPIK3CAPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |