Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124865 | 1.00 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBDDB1 | |
| SCHEMBL793560 | 0.83 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL20502398 | 0.83 | ALDH1A1 (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL13097259 | 0.83 | F10 (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL2940366 | 0.83 | MAP4K1 (0.50) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL1438679 | 0.83 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL10272402 | 0.83 | ALDH1A1 (0.52) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| Hydrochloric Acid SCHEMBL793754 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL8230773 | 0.82 | F10 (0.49) | PIK3CDPIK3CAPIK3CGPIK3CBF10 | |
| SCHEMBL198132 | 0.81 | PTGS2 (0.57) | F10PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111721858-B | Method for determining genotoxic impurities in rivaroxaban | 杭州华东医药集团新药研究院有限公司 | 2022-07-01 | — | — | CN | disclosed |