Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930730 | 0.76 | ALDH1A1 (0.37) | ALDH1A1RGS12MAPTKDM4EHPGD | |
| SCHEMBL31298381 | 0.72 | HTT (0.38) | ALDH1A1RGS12MAPTKDM4EJMJD6 | |
| SCHEMBL6930728 | 0.71 | ALDH1A1 (0.38) | ALDH1A1RGS12MAPTKDM4EHPGD | |
| SCHEMBL20364513 | 0.71 | LPO (0.39) | KDM4ELPOMCL1 | |
| SCHEMBL1822302 | 0.70 | ALDH1A1 (0.46) | ALDH1A1RGS12MAPTKDM4EHPGD | |
| SCHEMBL20368151 | 0.69 | HTT (0.41) | ALDH1A1RGS12MAPTKDM4ELPO | |
| SCHEMBL25061990 | 0.68 | ATM (0.54) | ALDH1A1MAPTHPGDNPC1LMNA | |
| SCHEMBL30544523 | 0.68 | TSHR (0.33) | ALDH1A1RGS12MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4002547 | 0.67 | TSHR (0.37) | KDM4ELPOMCL1 | |
| SCHEMBL9033147 | 0.67 | LPO (0.41) | KDM4ELPOMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973512-A1 | N-HYDROXY-2-(ALKYL, ARYL OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998037877-A1 | N-HYDROXY-2-(ALKYL, ARYL OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |