SCHEMBL823097

SCHEMBL823097

COC(=O)/C=C\C=C/C(=O)OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.75
HCAR2 Q8TDS4 2/20 0.75
KEAP1 Q14145 1/20 0.75
ALDH1A1 P00352 5/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
RECQL P46063 1/20 0.52
MAPT P10636 4/20 0.45
KDM4E B2RXH2 3/20 0.45
TDP1 Q9NUW8 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TYR P14679 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
TTR P02766 1/20 0.39
APP P05067 1/20 0.39
MEN1 O00255 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820946 1.00 NFE2L2 (0.75) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
SCHEMBL821014 1.00 NFE2L2 (0.75) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
SCHEMBL2944118 1.00 NFE2L2 (0.75) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
Carbon Monoxide SCHEMBL11053883 0.91 NFE2L2 (0.63) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
Methyl Sorbate SCHEMBL166359 0.89
Methyl Sorbate SCHEMBL821214 0.89
SCHEMBL11203918 0.89 HCAR2 (0.71) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
Methyl Sorbate SCHEMBL14764128 0.89 NFE2L2 (0.60) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
SCHEMBL13036666 0.89 NFE2L2 (0.60) NFE2L2HCAR2KEAP1ALDH1A1ALOX15
SCHEMBL11203915 0.89 HCAR2 (0.71) NFE2L2HCAR2KEAP1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4674574-A USING TERPOLYMERS; FOR GAS FRESH AND SEA WATER DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1987-06-23 US claimed
US-11518847-B2 Polymers and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2022-12-06 US disclosed
US-11459289-B2 Conversion of dicarboxylic acids to monomers and plasticizers ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2022-10-04 US disclosed
US-20200377443-A1 CONVERSION OF DICARBOXYLIC ACIDS TO MONOMERS AND PLASTICIZERS Alliance for Energy Innovation, LLC 2020-12-03 US disclosed
US-10793506-B2 Conversion of dicarboxylic acids to monomers and plasticizers ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2020-10-06 US disclosed
US-20200255368-A1 CONVERSION OF DICARBOXYLIC ACIDS TO MONOMERS AND PLASTICIZERS Alliance for Energy Innovation, LLC 2020-08-13 US disclosed
CN-106103395-B Low pressure synthesis of cyclohexanedimethanol and derivatives 伊士曼化工公司 2019-08-27 CN disclosed
CN-108083978-A The preparation process and device of cyclohexanedimethanol 万华化学集团股份有限公司 2018-05-29 CN disclosed
US-20170335031-A1 POLYMERS FROM MUCONIC ACID ISOMERS AND ITS DERIVATIVES PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2017-11-23 US disclosed
US-20170335031-A1 POLYMERS FROM MUCONIC ACID ISOMERS AND ITS DERIVATIVES PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2017-11-23 US disclosed
US-4073896-A Insecticide from dimethylmuconic acid SUN VENTURES, INC. (US) 1978-02-14 US disclosed
US-4058605-A Insecticides from dimethylmuconic acid SUN VENTURES, INC. (US) 1977-11-15 US disclosed
US-4012461-A DISSOLVING IN A SOLVENT, COOLING, SHEARING, ATOMIZING EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-03-15 US disclosed
US-3993713-A ATOMIZATION, SPRAY DRYING EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-11-23 US disclosed
US-3991112-A Methylated muconic acid hydrazides SUN RESEARCH AND DEVELOPMENT CO. (US) 1976-11-09 US disclosed
US-3991040-A Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these TEIJIN LIMITED (JA) 1976-11-09 US disclosed
US-3981957-A THERMOPLASTIC POLYMER EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-09-21 US disclosed
US-3937689-A ALLYL ESTERS OF BENZENE AND NAPHTHALENE DICARBOXYLIC ACIDS TEIJIN LTD. (JA) 1976-02-10 US disclosed
US-3931224-A Aromatic imidodicarboxylic acid diallyl esters, prepolymers thereof, cured resins thereof, and processes for producing these TEIJIN LIMITED (JA) 1976-01-06 US disclosed
US-3775089-A METHYLATED MUCONIC ACID HYDRAZIDES DONNELL A 1973-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377443-A1 CONVERSION OF DICARBOXYLIC ACIDS TO MONOMERS AND PLASTICIZERS TRRAP, HCAR2, SCD NFE2L2 403/4885HCAR2 2/4885KEAP1 1747/4885
US-11459289-B2 Conversion of dicarboxylic acids to monomers and plasticizers TRRAP, HCAR2, SCD NFE2L2 403/4885HCAR2 2/4885KEAP1 1747/4885
US-20200255368-A1 CONVERSION OF DICARBOXYLIC ACIDS TO MONOMERS AND PLASTICIZERS TRRAP, HCAR2, SCD NFE2L2 403/4885HCAR2 2/4885KEAP1 1747/4885
US-20170335031-A1 POLYMERS FROM MUCONIC ACID ISOMERS AND ITS DERIVATIVES SORD, SUCNR1, SLC16A7 NFE2L2 3457/4885HCAR2 372/4885KEAP1 3608/4885
US-10793506-B2 Conversion of dicarboxylic acids to monomers and plasticizers TRRAP, HCAR2, SCD NFE2L2 403/4885HCAR2 2/4885KEAP1 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.