Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AOC2 | O75106 | 2/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060481 | 0.90 | CACNA1I (0.60) | MEN1KMT2ACACNA1ICACNA1GCACNA1H | |
| SCHEMBL1057458 | 0.81 | CACNA1I (0.53) | MEN1KMT2ACACNA1ICACNA1GCACNA1H | |
| SCHEMBL1061577 | 0.74 | ALDH1A1 (0.54) | KMT2ACACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL1060494 | 0.73 | CACNA1H (0.56) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL1063110 | 0.72 | MAPT (0.52) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL1062362 | 0.72 | CACNA1I (0.63) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL1062626 | 0.72 | MAPT (0.51) | MEN1KMT2ACACNA1ICNR2LMNA | |
| SCHEMBL1062051 | 0.71 | ALDH1A1 (0.50) | KMT2ACACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL1062049 | 0.71 | WNT3A (0.55) | KMT2ACACNA1ICACNA1GCACNA1HCNR2 | |
| SCHEMBL1065313 | 0.71 | ALDH1A1 (0.62) | MEN1KMT2ACACNA1ICACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120729-A2 | PYRIDYL AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | disclosed |