Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | PI4KA | P42356 | 4/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25300074 | 0.74 | RAB9A (0.47) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL31114752 | 0.74 | RAB9A (0.47) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL8977446 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL4684501 | 0.70 | RAB9A (0.56) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL25303557 | 0.69 | PI4KA (0.59) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL31114602 | 0.68 | RAB9A (0.54) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL25305045 | 0.68 | RAB9A (0.54) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL8232579 | 0.68 | GRM5 (0.39) | ALDH1A1RAB9AMAPTTSHRTDP1 | |
| SCHEMBL8232666 | 0.68 | APP (0.36) | TSHRTDP1 | |
| SCHEMBL25258605 | 0.67 | RAB9A (0.53) | ALDH1A1KDM4ELMNAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084451-A1 | HYDANTOIN DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |