Sugi Predict

Sugi Predict / Compounds / SCHEMBL823296

SCHEMBL823296

SCHEMBL823296

COC(=O)/C(O)=C(\O)C(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.47
▸ EGLN1 Q9GZT9 1/20 0.43
▸ TET2 Q6N021 1/20 0.38
▸ TGFBR1 P36897 1/20 0.37
▸ TSHR P16473 5/20 0.37
▸ HCAR2 Q8TDS4 2/20 0.37
▸ KEAP1 Q14145 1/20 0.37
▸ NFE2L2 Q16236 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.33
▸ MGAM O43451 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ SI P14410 1/20 0.33
▸ MGAM2 Q2M2H8 1/20 0.33
▸ FFAR3 O14843 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ FYN P06241 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.32
▸ MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770999 1.00 ALDH1A1 (0.47) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL3185570 1.00 ALDH1A1 (0.47) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL8605808 0.90 ALDH1A1 (0.41) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL8607826 0.90 ALDH1A1 (0.41) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL12166161 0.90 ALDH1A1 (0.41) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL28386374 0.86 — —
SCHEMBL3048415 0.83 — —
SCHEMBL27713670 0.83 ALDH1A1 (0.41) ALDH1A1EGLN1TET2TGFBR1TSHR
SCHEMBL15131692 0.83 — —
SCHEMBL25855628 0.81 ALDH1A1 (0.39) ALDH1A1EGLN1TET2TGFBR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115256907-A High-temperature-resistant elastomer heat-shrinkable sleeve and preparation method thereof 大连联合高分子材料有限公司 2022-11-01 — — CN claimed
CN-114149546-A Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 史才军 2022-03-08 — — CN claimed
CN-110105503-A A kind of efficient diminishing polycarboxylate water-reducer of viscosity reduction type and preparation method thereof 湖南大学 2019-08-09 — — CN claimed
US-11744150-B2 Synthesis of aza-acenes as novel n-type materials for organic electronics UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-08-29 — — US disclosed
US-11744150-B2 Synthesis of aza-acenes as novel n-type materials for organic electronics UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-08-29 — — US disclosed
CN-115256907-A High-temperature-resistant elastomer heat-shrinkable sleeve and preparation method thereof 大连联合高分子材料有限公司 2022-11-01 — — CN disclosed
CN-115256907-A High-temperature-resistant elastomer heat-shrinkable sleeve and preparation method thereof 大连联合高分子材料有限公司 2022-11-01 — — CN disclosed
CN-114149546-A Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 史才军 2022-03-08 — — CN disclosed
US-20210313517-A1 SYNTHESIS OF AZA-ACENES AS NOVEL N-TYPE MATERIALS FOR ORGANIC ELECTRONICS UNITED STATES DEPARTMENT OF ENERGY 2021-10-07 — — US disclosed
CN-110105503-B Viscosity-reducing type efficient water-reducing polycarboxylate superplasticizer and preparation method thereof 湖南大学 2021-07-30 — — CN disclosed
EP-3566701-A1 DEUTERIUM SUBSTITUTED FUMARATE DERIVATIVES Biogen MA Inc. (US) 2019-11-13 — — EP disclosed
US-20040138451-A1 Epindolidione pigments CLARIANT FINANCE (BVI) LTD. (VG) 2004-07-15 — — US disclosed
CN-1491226-A Epindolidione pigments �����ﰲ�ز���(BVI)���޹�˾ 2004-04-21 — — CN disclosed
EP-1379527-A1 EPINDOLIDIONE PIGMENTS Clariant Finance (BVI) Limited (VG) 2004-01-14 — — EP disclosed
WO-2002062796-A1 EPINDOLIDIONE PIGMENTS CLARIANT FINANCE (BVI) LIMITED (VG) 2002-08-15 — — WO disclosed
EP-0801651-B1 HYDROXYMETHYLIMIDAZODIAZEPINES AND THEIR ESTERS HOFFMANN LA ROCHE (CH) 2001-07-11 — — EP disclosed
US-6174881-B1 USED AS ANXIOLYTIC AND/OR ANTICONVULSANT AND/OR MUSCLE RELAXANT AGENTS; SEDATIVES OR HYPNOSIS; WATER-SOLUBLE AMINE SALTS; FAST-ACTING HOFFMAN-LA ROCHE INC. 2001-01-16 — — US disclosed
CN-1168140-A Hydroxymethyl imidazodiazepine * and esters thereof HOFFMANN LA ROCHE (CH) 1997-12-17 — — CN disclosed
EP-0801651-A1 HYDROXYMETHYLIMIDAZODIAZEPINES AND THEIR ESTERS F. HOFFMANN-LA ROCHE AG (CH) 1997-10-22 — — EP disclosed
WO-1996020941-A1 HYDROXYMETHYLIMIDAZODIAZEPINES AND THEIR ESTERS F. HOFFMANN-LA ROCHE AG (CH) 1996-07-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210313517-A1 SYNTHESIS OF AZA-ACENES AS NOVEL N-TYPE MATERIALS FOR ORGANIC ELECTRONICS ACE2, ACE, AZI2 ALDH1A1 339/4885EGLN1 3327/4885TET2 98/4885
US-11744150-B2 Synthesis of aza-acenes as novel n-type materials for organic electronics ACE2, ACE, AZI2 ALDH1A1 339/4885EGLN1 3327/4885TET2 98/4885
US-20040138451-A1 Epindolidione pigments CCND2, CCND1, CCND3 ALDH1A1 50/4885EGLN1 4096/4885TET2 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.