Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631367 | 0.91 | ALDH1A1 (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3856731 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13631365 | 0.85 | RAD51 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8233776 | 0.84 | RAD51 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3866101 | 0.83 | RAD51 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3866107 | 0.82 | RAD51 (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL16747601 | 0.74 | MCHR1 (0.41) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL31305184 | 0.73 | POLB (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3308674 | 0.72 | GLS (0.44) | ALDH1A1MEN1KMT2AKDM4EHTR2C | |
| SCHEMBL6815441 | 0.72 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |