Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.58 |
| ▸ | FADS1 | O60427 | 2/20 | 0.55 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913770 | 0.88 | FADS1 (0.56) | GRM2FADS1 | |
| SCHEMBL2913774 | 0.88 | FADS1 (0.56) | GRM2FADS1 | |
| SCHEMBL2892191 | 0.86 | FADS1 (0.55) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL2892189 | 0.86 | FADS1 (0.55) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL2901244 | 0.86 | FADS1 (0.55) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL2893947 | 0.86 | FADS1 (0.55) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL2901243 | 0.86 | FADS1 (0.55) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL2915825 | 0.86 | FADS1 (0.60) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL2915828 | 0.86 | FADS1 (0.60) | GRM2FADS1PRSS12HTR2A | |
| SCHEMBL3484313 | 0.84 | FADS1 (0.54) | GRM2FADS1PRSS12HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007078523-A2 | 5-PHENYL-3-BENZYL-0XAZ0LIDIN-2-0NE DERIVATIVES AND RELATED COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | ASTRAZENECA AB (SE) | 2007-07-12 | — | — | WO | disclosed |