Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268509 | 0.86 | NR3C2 (0.41) | NR3C2KDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL13343039 | 0.86 | PDE4D (0.43) | NR3C2LMNAKDM4ECNR1GPR55 | |
| SCHEMBL8268769 | 0.84 | KDM5A (0.42) | NR3C2 | |
| SCHEMBL8234208 | 0.84 | KDM5A (0.42) | NR3C2 | |
| SCHEMBL8268750 | 0.83 | PTGS2 (0.49) | PTGS2ALDH1A1 | |
| SCHEMBL8268810 | 0.79 | ALDH1A1 (0.42) | NR3C2PIK3CDPTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5407578 | 0.76 | PDE4D (0.44) | LMNAKDM4EMCL1 | |
| SCHEMBL3596224 | 0.76 | PDE4D (0.44) | LMNAKDM4EMCL1 | |
| SCHEMBL8268748 | 0.76 | PIK3CD (0.38) | NR3C2LMNAPIK3CDMAPT | |
| SCHEMBL8268749 | 0.76 | PIK3CD (0.42) | NR3C2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123953-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2007-11-01 | — | — | WO | disclosed |