Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984933 | 0.74 | LMNA (0.48) | MAPTLMNATDP1KMT2APOLB | |
| SCHEMBL15654783 | 0.72 | MAPT (0.40) | MAPTLMNATDP1HTTKMT2A | |
| SCHEMBL616370 | 0.72 | MAPT (0.46) | MAPTLMNATDP1KMT2APOLB | |
| SCHEMBL987687 | 0.72 | MAPT (0.41) | MAPTLMNATDP1KMT2APOLB | |
| SCHEMBL3557238 | 0.72 | LMNA (0.42) | MAPTLMNATDP1KMT2APOLB | |
| SCHEMBL3557236 | 0.70 | ALDH1A1 (0.41) | LMNAKMT2APOLBCYP2C19RXFP1 | |
| SCHEMBL15654770 | 0.70 | GRM5 (0.42) | MAPTLMNATDP1KMT2APOLB | |
| SCHEMBL3704151 | 0.69 | ALDH1A1 (0.44) | MAPTLMNATDP1HTTPOLB | |
| SCHEMBL10104881 | 0.66 | MAPT (0.40) | MAPTLMNATDP1HTTKMT2A | |
| SCHEMBL8232807 | 0.65 | ERN1 (0.41) | MAPTLMNATDP1POLBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087443-A2 | VINYL-PHENYL DERIVATIVES FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |