Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646343 | 0.91 | RAB9A (0.49) | HPGDKDM4EMEN1KMT2AMAPT | |
| SCHEMBL8229772 | 0.88 | TP53 (0.38) | KDM4EKMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8234330 | 0.86 | MAPT (0.43) | KDM4EMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8235951 | 0.83 | SMN1; SMN2 (0.38) | HPGDKDM4ESMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8234047 | 0.83 | RAB9A (0.43) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL8236420 | 0.82 | MAPT (0.46) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL11940274 | 0.81 | IL2 (0.41) | KDM4EMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL8233863 | 0.81 | EPHX2 (0.42) | HPGDKDM4ESMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL648069 | 0.80 | KMT2A (0.43) | KDM4EMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8236393 | 0.80 | IL2 (0.41) | KDM4ESMN1; SMN2RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109362-A2 | BENZOIMIDAZOLYL-PARAZINE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-09-27 | — | — | WO | disclosed |