Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838269 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL1620488 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4573337 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16478505 | 0.78 | NOTUM (0.48) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL4343120 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL676377 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9363173 | 0.78 | KDM4E (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL118713 | 0.78 | KDM4E (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5663652 | 0.78 | KDM4E (0.60) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5535834 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105019013-A | Blue-light emitting monocrystalline material preparation method | UNIV TAIYUAN TECHNOLOGY | 2015-11-04 | — | — | CN | claimed |
| CN-103664811-B | (1H-1,2,4-triazol-1-yl) aryl compound and preparation method thereof | IHARA CHEMICAL IND CO. (JP) | 2015-09-16 | — | — | CN | claimed |
| EP-2226317-B1 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND, AND PROCESS FOR PRODUCTION THEREOF | IHARA CHEMICAL IND CO (JP) | 2015-08-12 | — | — | EP | claimed |
| US-8648207-B2 | Aryl (1H-1,2,4-triazol-1-yl) compound, and process for production thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-02-11 | — | — | US | claimed |
| US-20130023666-A1 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND, AND PROCESS FOR PRODUCTION THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-01-24 | — | — | US | claimed |
| US-20100256386-A1 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND AND PROCESS FOR PRODUCTION THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-07 | — | — | US | claimed |
| EP-2226317-A1 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND, AND PROCESS FOR PRODUCTION THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-09-08 | — | — | EP | claimed |
| EP-3483144-B1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROLLING AGENT CONTAINING SAME | SUMITOMO CHEMICAL CO (JP) | 2023-10-11 | — | — | EP | disclosed |
| US-11779018-B2 | Heterocyclic compound and arthropod pest control composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| US-11779018-B2 | Heterocyclic compound and arthropod pest control composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| US-11690378-B2 | Substituted pyridines as noxious arthropod control agents | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-11690378-B2 | Substituted pyridines as noxious arthropod control agents | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-07-04 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
| US-6613747-B2 | Erythromycins to treat community-acquired pneumonia and upper and lower respiratory tract, skin and soft tissue, hospital-acquired lung, bone and joint infections; Staphyloccus; Enterococcus; Moraxella; Hemophilus; antibiotic resistance | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-09-02 | — | — | US | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |
| US-6472372-B1 | 6-O-Carbamoyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICALS, INC. | 2002-10-29 | — | — | US | disclosed |
| US-20020115620-A1 | 6-0-carbamoyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-08-22 | — | — | US | disclosed |
| EP-1003505-A1 | HETEROCYCLIC VINYLETHERS AGAINST NEUROLOGICAL DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999008678-A1 | HETEROCYCLIC VINYLETHERS AGAINST NEUROLOGICAL DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256386-A1 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND AND PROCESS FOR PRODUCTION THEREOF | CYP1A1, CYP2S1, NAT1 | SMN1; SMN2 4288/4885KDM4E 2741/4885ALDH1A1 217/4885 |
| US-11690378-B2 | Substituted pyridines as noxious arthropod control agents | COX6C, C5, COX6B1 | SMN1; SMN2 2016/4885KDM4E 1244/4885ALDH1A1 1417/4885 |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | SMN1; SMN2 4073/4885KDM4E 18/4885ALDH1A1 2109/4885 |
| US-11779018-B2 | Heterocyclic compound and arthropod pest control composition containing same | C5, PRXL2A, NOX3 | SMN1; SMN2 2926/4885KDM4E 869/4885ALDH1A1 2765/4885 |
| US-20130023666-A1 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND, AND PROCESS FOR PRODUCTION THEREOF | CYP1B1, CYP1A1, AOC3 | SMN1; SMN2 4111/4885KDM4E 3697/4885ALDH1A1 99/4885 |
| US-20020115620-A1 | 6-0-carbamoyl ketolide antibacterials | Q6ZSR9, HK1, KDM4E | SMN1; SMN2 4281/4885KDM4E 3/4885ALDH1A1 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.