Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3385416 | 0.98 | S100B (0.61) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL3385418 | 0.98 | S100B (0.61) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL20163179 | 0.92 | S100B (0.55) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL8061571 | 0.86 | S100B (0.49) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL27568179 | 0.86 | S100B (0.60) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL11443253 | 0.85 | S100B (0.59) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL5491814 | 0.84 | S100B (0.46) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL9114225 | 0.84 | S100B (0.46) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL11441484 | 0.83 | S100B (0.58) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL11742876 | 0.83 | S100B (0.58) | S100BALDH1A1L3MBTL1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2853293-B1 | Thioninium compounds and their use | WISTA LAB LTD (SG) | 2017-11-22 | — | — | EP | disclosed |
| EP-2001556-B1 | THIONINIUM COMPOUNDS AND THEIR USE | WISTA LAB LTD (SG) | 2014-10-01 | — | — | EP | disclosed |
| US-8263589-B2 | Inhibitors of protein aggregation | WISTA LABORATORIES LTD. (SG) | 2012-09-11 | — | — | US | disclosed |
| US-8263589-B2 | Inhibitors of protein aggregation | WISTA LABORATORIES LTD. (SG) | 2012-09-11 | — | — | US | disclosed |
| US-7737138-B2 | Methods of treatment of a tauopathy condition comprising the use of thioninium compounds | WISTA LABORATORIES LTD. (SG) | 2010-06-15 | — | — | US | disclosed |
| US-7737138-B2 | Methods of treatment of a tauopathy condition comprising the use of thioninium compounds | WISTA LABORATORIES LTD. (SG) | 2010-06-15 | — | — | US | disclosed |
| US-20090209526-A1 | INHIBITORS OF PROTEIN AGGREGATION | WISTA LABORATORIES LTD | 2009-08-20 | — | — | US | disclosed |
| US-20090209526-A1 | INHIBITORS OF PROTEIN AGGREGATION | WISTA LABORATORIES LTD | 2009-08-20 | — | — | US | disclosed |
| WO-2007110629-A1 | INHIBITORS OF PROTEIN AGGREGATION | WISTA LABORATORIES LTD (SG) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110630-A1 | THIONINIUM COMPOUNDS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2007-10-04 | — | — | WO | disclosed |
| EP-0643327-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-4233399-A | Photographic elements containing amino-substituted hydroxy-pyridones | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-11-11 | — | — | US | disclosed |
| US-4182886-A | OPTICAL FILTERS IN COLOR PHOTOGRAPHY | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209526-A1 | INHIBITORS OF PROTEIN AGGREGATION | SNCA, PARK7, HTT | S100B 261/4885ALDH1A1 3469/4885L3MBTL1 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.