Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730306 | 0.92 | KMT2A (0.49) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL1104649 | 0.86 | MAOB (0.56) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL1057910 | 0.86 | KMT2A (0.51) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL27808961 | 0.85 | ALDH1A1 (0.55) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL6153301 | 0.83 | MAOB (0.48) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL9782658 | 0.83 | MAOB (0.52) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL10969822 | 0.83 | MAOB (0.52) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL6865970 | 0.82 | MAOB (0.52) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL1759352 | 0.82 | MAOB (0.55) | KMT2AMEN1MAOBALDH1A1HTT | |
| SCHEMBL5583436 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1MAOBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079130-A2 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2007-07-12 | — | — | WO | disclosed |