Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950805 | 0.82 | BCHE (0.50) | SMN1; SMN2NPC1KDM4EALDH1A1HTR1A | |
| SCHEMBL7776226 | 0.78 | LMNA (0.54) | SMN1; SMN2KMT2ALMNANPC1MEN1 | |
| SCHEMBL3301381 | 0.78 | ABCB1 (0.60) | POLBSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL8092420 | 0.77 | KMT2A (0.54) | KMT2ANPC1MAPTMEN1KDM4E | |
| SCHEMBL31552456 | 0.77 | SMN1; SMN2 (0.71) | POLBSMN1; SMN2KMT2ALMNAL3MBTL1 | |
| SCHEMBL6744642 | 0.76 | SMN1; SMN2 (0.70) | POLBSMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL11434004 | 0.74 | CYP19A1 (0.50) | POLBKMT2AMAPTMEN1KDM4E | |
| SCHEMBL6743332 | 0.74 | POLB (0.62) | POLBSMN1; SMN2KMT2ALMNAL3MBTL1 | |
| SCHEMBL29639215 | 0.74 | KMT2A (0.54) | KMT2ANPC1MEN1KDM4EALDH1A1 | |
| SCHEMBL991380 | 0.74 | KMT2A (0.54) | KMT2ANPC1MEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044297-A2 | SOLID SUPPORT MATERIALS | Cambridge Drug Discovery Limited (GB) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999032705-A2 | SOLID SUPPORT MATERIALS | CAMBRIDGE DRUG DISCOVERY LIMITED (GB) | 1999-07-01 | — | — | WO | disclosed |