Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 10/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239838 | 0.87 | F2 (0.46) | F2MEN1KMT2ACMA1PRSS1 | |
| SCHEMBL12605461 | 0.84 | F2 (0.44) | F2CMA1PRSS1 | |
| SCHEMBL16329136 | 0.84 | F2 (0.44) | F2CMA1PRSS1 | |
| SCHEMBL12606101 | 0.81 | CMA1 (0.40) | F2CMA1PRSS1ELANE | |
| SCHEMBL23832915 | 0.79 | ACE (0.49) | F2CMA1 | |
| SCHEMBL6077122 | 0.79 | ACE (0.49) | F2CMA1 | |
| SCHEMBL13399702 | 0.79 | ACE (0.49) | F2CMA1 | |
| SCHEMBL20681647 | 0.79 | ACE (0.49) | F2CMA1 | |
| SCHEMBL20681648 | 0.79 | ACE (0.49) | F2CMA1 | |
| SCHEMBL12606207 | 0.79 | F2 (0.39) | F2CMA1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089618-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2007-08-09 | — | — | WO | disclosed |