Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 5/20 | 0.42 |
| ▸ | CMA1 | P23946 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236627 | 0.87 | F2 (0.44) | F2ELANECMA1MEN1KMT2A | |
| SCHEMBL806061 | 0.81 | ELANE (0.45) | ELANECMA1 | |
| SCHEMBL14639776 | 0.81 | NR1I2 (0.52) | — | |
| SCHEMBL26121717 | 0.79 | ACE (0.51) | F2ELANECMA1 | |
| SCHEMBL159043 | 0.79 | ACE (0.51) | F2ELANECMA1 | |
| SCHEMBL806133 | 0.79 | ACE (0.51) | F2ELANECMA1 | |
| SCHEMBL1300341 | 0.79 | ACE (0.51) | F2ELANECMA1 | |
| SCHEMBL10141143 | 0.78 | CMA1 (0.41) | F2CMA1PRSS1 | |
| SCHEMBL8046113 | 0.78 | KLK5 (0.51) | ELANECMA1 | |
| SCHEMBL8055611 | 0.78 | ELANE (0.42) | F2ELANECMA1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089618-A2 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2007-08-09 | — | — | WO | disclosed |