Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236031 | 0.96 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTCXCR3TP53GABRA2 | |
| SCHEMBL8228005 | 0.91 | TSHR (0.44) | SMN1; SMN2MAPTCXCR3 | |
| SCHEMBL8236364 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTCXCR3 | |
| SCHEMBL8236760 | 0.90 | MAPT (0.43) | SMN1; SMN2MAPTCXCR3TP53 | |
| SCHEMBL8228518 | 0.88 | PSMB5 (0.42) | SMN1; SMN2MAPTCXCR3 | |
| SCHEMBL8228164 | 0.87 | THRB (0.46) | SMN1; SMN2MAPTCXCR3TP53THRB | |
| SCHEMBL8233163 | 0.86 | MAPT (0.47) | SMN1; SMN2MAPTCXCR3TP53 | |
| SCHEMBL8234229 | 0.85 | CXCR3 (0.49) | CXCR3 | |
| SCHEMBL8228511 | 0.85 | CXCR3 (0.45) | MAPTCXCR3FNTAFNTB | |
| SCHEMBL8236040 | 0.85 | MAPT (0.47) | MAPTCXCR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |