Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311666 | 0.80 | TSHR (0.53) | TDP1ALDH1A1 | |
| SCHEMBL5936821 | 0.77 | — | — | |
| SCHEMBL5936822 | 0.77 | — | — | |
| SCHEMBL5936824 | 0.77 | — | — | |
| SCHEMBL23230873 | 0.76 | LMNA (0.35) | TDP1ALDH1A1 | |
| SCHEMBL14724844 | 0.76 | — | — | |
| SCHEMBL279294 | 0.74 | — | — | |
| SCHEMBL9911578 | 0.74 | — | — | |
| SCHEMBL21063885 | 0.74 | LDHA (0.32) | — | |
| SCHEMBL24786140 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093880-A2 | NOVEL PYRONE-INDOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | NEURIM PHARMACEUTICALS (1991) LTD. (US) | 2007-08-23 | — | — | WO | disclosed |