Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20220676 | 1.00 | THRB (0.30) | THRBMEN1KMT2A | |
| SCHEMBL727318 | 0.97 | — | — | |
| SCHEMBL277534 | 0.97 | — | — | |
| Ethane SCHEMBL28302807 | 0.95 | THRB (0.30) | THRBMEN1KMT2A | |
| SCHEMBL2461915 | 0.90 | — | — | |
| Glycerin SCHEMBL27486080 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL19067421 | 0.78 | THRB (0.41) | THRBMEN1KMT2A | |
| SCHEMBL24760387 | 0.77 | GAA (0.33) | THRBMEN1KMT2A | |
| SCHEMBL28872817 | 0.76 | KDM1A (0.37) | — | |
| SCHEMBL20526081 | 0.75 | F2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |