Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976283 | 0.89 | CTSB (0.41) | CTSBCTSSHDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL4522873 | 0.88 | CTSB (0.41) | CTSBCTSS | |
| Hydrochloric Acid SCHEMBL1683100 | 0.88 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL7993405 | 0.86 | CTSB (0.38) | CTSBCTSS | |
| SCHEMBL11976284 | 0.82 | CTSB (0.42) | CTSBCTSSHDAC4HDAC1 | |
| SCHEMBL13082504 | 0.82 | CTSB (0.42) | CTSBCTSSHDAC4HDAC1 | |
| SCHEMBL13435803 | 0.82 | CTSB (0.38) | CTSBCTSS | |
| SCHEMBL8249221 | 0.81 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL7914476 | 0.81 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL15509452 | 0.81 | CTSB (0.41) | CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |