Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 9/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15509453 | 1.00 | CTSB (0.41) | CTSBCTSSPSMB9PSMB8 | |
| SCHEMBL15509452 | 1.00 | CTSB (0.41) | CTSBCTSSPSMB9PSMB8 | |
| SCHEMBL15509451 | 1.00 | CTSB (0.41) | CTSBCTSSPSMB9PSMB8 | |
| SCHEMBL8249221 | 1.00 | CTSB (0.41) | CTSBCTSSPSMB9PSMB8 | |
| SCHEMBL13502758 | 0.89 | CTSB (0.40) | CTSBCTSS | |
| SCHEMBL8246800 | 0.88 | CTSB (0.34) | CTSBCTSSPSMB9PSMB8 | |
| SCHEMBL11976284 | 0.88 | CTSB (0.42) | CTSBCTSS | |
| SCHEMBL11976283 | 0.88 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL13082504 | 0.88 | CTSB (0.42) | CTSBCTSS | |
| Hydrochloric Acid SCHEMBL4522873 | 0.87 | CTSB (0.41) | CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088394-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-08-05 | — | — | WO | disclosed |