Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 2/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239476 | 0.84 | TSHR (0.39) | STIM1ORAI1GPR3TSHRCTNNB1 | |
| SCHEMBL13367746 | 0.76 | STIM1 (0.40) | STIM1ORAI1GPR3TSHRCTNNB1 | |
| SCHEMBL16044114 | 0.76 | GPR3 (0.34) | GPR3CTNNB1WNT3A | |
| SCHEMBL8236665 | 0.74 | CD44 (0.43) | STIM1ORAI1GPR3TSHR | |
| SCHEMBL1702518 | 0.74 | STIM1 (0.33) | STIM1ORAI1GPR3TSHRCTNNB1 | |
| SCHEMBL12279630 | 0.74 | STIM1 (0.33) | STIM1ORAI1GPR3TSHRCTNNB1 | |
| SCHEMBL31457665 | 0.74 | AHR (0.33) | GPR3CTNNB1WNT3A | |
| SCHEMBL1859168 | 0.74 | GPR3 (0.33) | GPR3CTNNB1WNT3A | |
| SCHEMBL16076086 | 0.74 | TSHR (0.42) | STIM1ORAI1GPR3TSHR | |
| SCHEMBL16044169 | 0.74 | ATP4A (0.36) | GPR3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089034-A1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |