Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 15/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247064 | 0.86 | DPP4 (0.34) | GAAALOX15HSD17B10 | |
| SCHEMBL8237366 | 0.79 | DPP4 (0.31) | GAAALOX15HSD17B10PPIA | |
| SCHEMBL13830431 | 0.78 | GAA (0.32) | CHEK1PARP1MAP2K1GAAALOX15 | |
| SCHEMBL8247123 | 0.78 | DPP4 (0.33) | GAAALOX15HSD17B10 | |
| SCHEMBL15593591 | 0.76 | AKR1C3 (0.32) | — | |
| SCHEMBL8171994 | 0.76 | — | — | |
| SCHEMBL11975940 | 0.76 | HDAC4 (0.33) | CHEK1PARP1MAP2K1GAAALOX15 | |
| SCHEMBL8249373 | 0.75 | DPP4 (0.37) | GAAALOX15HSD17B10 | |
| SCHEMBL8247433 | 0.75 | — | — | |
| SCHEMBL8185437 | 0.74 | ADRB3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015824-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2007-02-08 | — | — | WO | disclosed |